The link leads to a 2021 paper in Frontiers in Nutrition by Marleen van Baak and colleagues, examining physical activity, weight loss, and weight maintenance within a large European trial called DiOGenes. And the figure of 1,121 does appear in it — once, in the Subjects section, describing how many people were enrolled in the parent trial. It is not the number of people in any analysis the paper actually reports.
The paper is completely open about this. In the researchers' own words: "However, not all data were available at all time points, especially the data on PA were missing in many participants. Therefore, the number of subjects will differ in the different analyses. Complete body weight and PA data were available for 193 participants (76M/117F)." Nothing was hidden. The caveat was simply left behind somewhere between the paper and the feed.
Once you start counting, six different sample sizes appear across the paper's analyses, and the one that matters for the maintenance claim is not the largest.
The Figure That Matches Nothing
There is a second wrinkle, and it is the one we cannot resolve. The parent DiOGenes trial published its own participant flow in the New England Journal of Medicine in 2010, and that report states that 1,209 adults were screened, 938 entered the low-calorie-diet phase, 773 were randomly assigned to a maintenance diet, and 548 completed the study. None of those numbers is 1,121, and neither paper explains the gap. We are reporting it as an open discrepancy rather than guessing at a cause, because guessing is how this kind of thing starts.