Best Anti-Snoring Mouth Guards and MADs Ranked by Type
A Practical Guide to Choosing the Right Device for Your Sleep, Your Mouth, and Your Bed Partner's Sanity
By
Published: May 26, 2026
Credit: Daily Vitality
Key Takeaways
•The best snoring mouthpiece for you depends less on the brand and more on the type of device that fits your mouth, dental history, and daily routine.
•Five categories cover almost every snoring situation, from a simple boil-and-bite mandibular advancement device to a custom appliance fitted by a sleep dentist.
•Loud snoring with witnessed pauses in breathing, gasping, or daytime sleepiness is a sign to talk to a doctor, not buy another mouthpiece.
There is a particular kind of late-night research that begins with a gentle elbow to the ribs and ends, around midnight, with a browser full of mouthpiece tabs. If that is you — or you are doing this reconnaissance on behalf of someone who keeps insisting they don't snore — you have probably already noticed that most "best anti-snoring mouthpiece" lists rank brands. Brand A versus Brand B versus Brand C, ten in a row, with star ratings that all somehow land between 4.6 and 4.9.
The trouble with that format is that it skips the question that actually matters. Snoring mouthpieces are not all the same kind of thing. A boil-and-bite mouth guard you mold in your kitchen, a no-fuss device that ships in two sizes, a custom appliance built from a digital scan of your teeth, and a small soft device that holds the tip of your tongue forward by suction are four genuinely different products. They solve overlapping problems in different ways, suit different mouths, and come with different trade-offs. Once you know which type you need, picking the right brand becomes much easier.
This guide walks through the five main categories of anti-snoring oral appliances, with one clear top pick in each, the runners-up worth knowing about, and the honest trade-offs you should weigh before reaching for your wallet. It also includes a section on the signals that mean a mouthpiece is the wrong tool entirely, and the conversation you should be having with a sleep specialist instead. The aim is simple: less time scrolling, more time sleeping.
How To Think About the Five Categories
Before getting into the picks, it helps to understand what these devices actually do. Most anti-snoring mouthpieces work in one of two mechanical ways. A mandibular advancement device, or MAD, holds your lower jaw slightly forward while you sleep, which opens up the space behind the tongue where snoring vibration usually happens. A tongue-stabilizing device, sometimes called a tongue-retaining device, instead uses gentle suction to hold the tip of your tongue forward, which does the same job from a different angle. A hybrid combines both. The Sleep Foundation's overview of anti-snoring mouthpieces describes these as the two dominant categories, with hybrid designs forming a smaller third lane.
Within those mechanisms, the categories sort themselves out by how the device is fitted to your mouth. That is the dimension that matters most for comfort, effectiveness, and price.
A few criteria are worth carrying with you as you read. First, anti-snoring intraoral devices in the United States should be FDA-cleared — that means they have been reviewed under the FDA's 510(k) pathway as Class II medical devices, per the agency's special controls guidance for intraoral devices for snoring and obstructive sleep apnea. Cleared is the correct word; "FDA-approved" is a stricter standard that most over-the-counter mouthpieces have not been through. Second, look for devices designed by or in consultation with dentists. Third, look for a real money-back trial of at least 30 nights, because the only way to know a mouthpiece fits is to actually sleep in it for a couple of weeks. Fourth, take the brand's customer reviews seriously, especially the negative ones — a device that quietly tolerates honest criticism is usually better than one that hides behind a perfect star average. Finally, think in terms of cost per night of use rather than sticker price.
With those criteria in mind, here is how the five categories shake out, and which device deserves the top spot in each.
Boil-and-Bite Adjustable Mouth Guards
What This Type Is
A boil-and-bite mandibular advancement device is the most common starting point for over-the-counter snoring relief, and for good reason. You drop the device into hot water for a few seconds until it softens, then bite into it gently so the plastic molds to the shape of your teeth. Once it cools, you have a personalized fit at a fraction of the cost of a lab-made appliance. The better designs in this category also let you adjust how far your lower jaw is held forward, often in one-millimeter steps, so you can find the smallest amount of advancement that quiets the snoring without leaving your jaw aching in the morning.
Top Pick: SnoreRx Plus
If you want one device to try first in this category, SnoreRx Plus earns the recommendation. It is sold on the manufacturer's site for $99.99, with a 30-night money-back guarantee on direct purchases. The mechanism is the standout feature: a calibrated slider lets you advance your lower jaw in one-millimeter increments up to six millimeters total, and the brand recommends sitting at each new setting for at least three to five nights before moving up. That patience pays off, because most users land somewhere between three and five millimeters of advancement and a slower titration usually means less morning soreness.
The Plus version improves on the original SnoreRx in two practical ways. The hinged design allows your jaw to open slightly while you sleep, which matters a great deal if you tend to mouth-breathe or wake up with a dry throat. And the upper and lower trays detach for cleaning, which is the kind of small design choice you genuinely appreciate three weeks in. The device is made from medical-grade copolymer, BPA-free and latex-free, and the boil-and-bite process gives a snug fit without needing a dental appointment.
Where it falls short — and you should hear this before you buy — is in the customer experience around fit and returns. Third-party review scores for the brand have been mixed, with a meaningful share of complaints focused on the customer service side rather than the device itself. The honest read is that the engineering is genuinely best-in-class for an over-the-counter MAD, but you should plan to use your trial window with intent. Wear it for the full 30 nights if you can, and if it is not working by the end, actually start the return process rather than letting the window quietly close.
Worth Knowing in This Category
The closest runner-up is VitalSleep, priced more affordably and offering its own adjustment system that advances the jaw between zero and eight millimeters in one-millimeter increments. That extra advancement range is genuinely useful if six millimeters of forward jaw position turns out not to be enough for you, and the device comes in two sizes — usually marketed as men's and women's — which matters more than you might expect, because jaw width varies a lot between people. The trade-off is that the adjustment mechanism feels a little less refined than SnoreRx's calibrated slider, and some users find the device slightly bulkier in the mouth.
If you are shopping at a tighter budget, the SmartGuard RX is worth looking up. It is a simpler boil-and-bite design, FDA-cleared for adults eighteen and older, with a hinged construction that allows the mouth to open and a smaller advancement range from a neutral starting point. It will not give you the millimeter-level precision of SnoreRx Plus or the long advancement runway of VitalSleep, but for many straightforward snorers it does the basic job at a friendly price.
Tip
When you first start wearing any boil-and-bite MAD, set the advancement as small as possible for the first few nights and step it up only if snoring continues. Smaller advancement that you can actually tolerate beats more aggressive advancement that you abandon after a week.
Pre-Formed Multi-Size Mouth Guards
What This Type Is
If the idea of boiling and biting a mouthpiece on your kitchen counter sounds like a lot to ask at midnight, this category exists for you. Pre-formed mouth guards ship in two or more fixed sizes, each with a different amount of jaw advancement built in. You pick the one that fits and start sleeping in it immediately. There is no molding, no calibration, and almost no learning curve. The trade-off is that you are choosing from a small menu of fixed positions rather than dialing in your own, so the fit will not be as personalized as a boil-and-bite or custom appliance.
Top Pick: ZQuiet 2-Size Starter Pack
The clearest top pick in this category is the ZQuiet 2-Size Starter Pack, which is the standout because it solves the central problem of the category cleanly. The pack includes two pre-formed mouthpieces in different advancement positions, marketed as Level 1 and Level 2. Most people start with the milder size and move to the stronger one if needed, which gives you a built-in plan B without having to buy a second product. Pricing typically lands in the mid-range for the category and the brand frequently runs promotions, so it is worth checking the current price the day you buy.
The design itself is genuinely thoughtful. ZQuiet's "living hinge" architecture lets your jaw open and close while you wear the device, which means you can breathe through your mouth and even take a sip of water without removing it. The mouthpiece is made from soft, BPA-free material and the front of the device is open, so the experience feels much less claustrophobic than the closed-shell mouthguards some people remember from sports. There is no boiling, no molding, no calibration screw to fuss with. You take it out of the box, try it on, and go to sleep.
Where ZQuiet falls short is the same thing that makes it appealing: there is no millimeter-by-millimeter adjustment. You are choosing between two fixed positions, and if your jaw would optimally sit somewhere in between, there is no way to land there. Some people also find both sizes a bit bulky, especially if you have a smaller mouth. The trial window is the only honest way to find out which category you fall into.
Note
Pre-formed mouth guards are also a good travel companion if you already use a boil-and-bite at home. Keeping one of these in a toiletry bag means you do not have to worry about losing or breaking the custom-fitted device you actually like.
Custom Dentist-Fitted Mouth Guards
What This Type Is
This is the category most people skip past because the over-the-counter options are cheaper and faster. That is fair if your snoring is mild and otherwise unbothersome, but if you have been snoring loudly for years, if your partner has mentioned any pauses or gasps, or if a basic MAD has only half-solved the problem, this category is worth taking seriously. A custom dentist-fitted oral appliance is built specifically for your mouth from impressions or a digital scan of your teeth, fabricated in a dental lab, and adjusted by a dentist who has trained in dental sleep medicine. It is what the joint clinical practice guideline from the American Academy of Sleep Medicine and the American Academy of Dental Sleep Medicine actually has in mind when it recommends "oral appliance therapy" for snoring and obstructive sleep apnea — not the boxed devices on Amazon.
Custom appliances have the best clinical track record. They last longer, typically three to five years with proper care. They achieve better adherence because they are more comfortable. And they come with a clinician monitoring your fit over time, which is the only realistic way to catch and manage the small bite changes that can happen with long-term mandibular advancement.
Top Pick: SomnoDent (SomnoMed)
The SomnoDent family from SomnoMed is the most widely prescribed line of custom oral appliances in the United States, and it is the safest pick to recommend without knowing the specifics of your bite. The devices are made from medical-grade acrylic, fabricated using CAD/CAM technology from impressions or digital scans of your teeth, and come in several variants — Flex and Avant among them — that your dentist will choose between based on your jaw anatomy and how much advancement you need.
You should expect typical out-of-pocket costs in the United States to fall somewhere between $1,500 and $3,000, depending on your dentist's fees, your region, and how your insurance treats the prescription. Medical insurance often covers oral appliance therapy when it is prescribed for diagnosed obstructive sleep apnea, using the same criteria insurers use for CPAP. Coverage for primary snoring without an apnea diagnosis is much less common and usually does not happen. The full process — sleep study if your insurance requires one, dental sleep medicine consult, impressions, lab fabrication that typically takes two to four weeks, fitting appointment, and follow-up titration visits — takes a couple of months end to end.
Where this category falls short is exactly what you would expect: time, money, and access. It is not the right choice if you simply want to try something tonight. And it does require a dentist with dental sleep medicine training within reasonable driving distance, which not every part of the country has. But if your snoring is severe, persistent, or possibly hiding undiagnosed sleep apnea, this is the path that the clinical evidence supports most strongly.
Worth Knowing in This Category
If your dentist offers it, the Narval CC by ResMed is a lighter, more discreet alternative to the SomnoDent line. It is a custom CAD/CAM-milled nylon appliance designed to minimize the bulk and dental side effects that come with bigger acrylic devices. Manufacturer-sponsored research, including the ORCADES study, reports treatment success rates — defined as at least a 50% reduction in baseline apnea-hypopnea index — of around 79% overall, with approximately 84% success in patients with moderate obstructive sleep apnea. As with any manufacturer-funded data, take the numbers as directional rather than definitive, but the underlying design choice toward a lighter, flexible appliance is genuinely well-regarded among sleep dentists.
Important
If a partner has ever witnessed you stop breathing, gasp, or choke during sleep, please do not start with an over-the-counter mouthpiece. Talk to your primary care doctor about a sleep study first. Untreated sleep apnea has real cardiovascular consequences, and a $90 mouthpiece is not the place to be making that diagnosis on your own.
Tongue-Stabilizing Devices
What This Type Is
A tongue-stabilizing device, sometimes still called a tongue-retaining device, is a small, soft, flexible piece of medical-grade plastic or silicone that uses gentle suction to hold the tip of your tongue forward while you sleep. It does not touch your jaw, does not press against your teeth, and does not advance your bite. That makes it the right answer for several specific situations that disqualify mandibular advancement devices entirely: if you wear dentures, if you have a diagnosed temporomandibular joint disorder, if your dental work is too extensive for a MAD to grip safely, or if your snoring is being driven mostly by your tongue falling back into your airway rather than by jaw position. As the American Sleep Apnea Association explains in its overview of tongue-retaining devices, tongue-stabilizing designs occupy a small but genuinely useful corner of the market.
Top Pick: Good Morning Snore Solution
The clearest recommendation in this category is the Good Morning Snore Solution. It is sold by the manufacturer as a soft, clear device made from medical-grade plastic resin, FDA-cleared for over-the-counter use as an aid in reducing snoring. The fitting process is one of the simplest in any anti-snoring category: you squeeze the small bulb, slide the tip of your tongue into the opening, and release. The bulb creates a gentle vacuum that holds your tongue in place all night. There is nothing to mold, no calibration, and no learning curve beyond getting used to the sensation.
Pricing typically falls in the $90 to $130 range depending on the pack you choose and whether the brand is currently running a promotion, and the company offers a 30-day satisfaction guarantee on direct purchases. The reason it earns the category pick is that it is the right device for a clearly defined set of people who genuinely cannot use a MAD safely, and within that audience it has the most consistent track record and the cleanest user experience.
The clinical evidence for tongue-stabilizing devices is real but more modest in volume than for MADs. One frequently cited study on a customized tongue-retaining device found that the apnea-hypopnea index dropped from about 38 to 14 events per hour and subjective snoring intensity fell by roughly 68%, with about half of patients still using the device at five years of follow-up. That long-term adherence figure is honest and worth knowing: tongue-stabilizing devices work for many people, but they ask more of you in terms of getting used to the sensation than a MAD does. Tongue soreness in the first week is common as you adjust, and excess saliva is too. Both usually settle down, but a small share of users decide the device is not for them and use the trial window to return it.
If you have suspected obstructive sleep apnea, the manufacturer explicitly advises against treating it with the device alone and directs you to see a healthcare practitioner. That advice is worth following.
Hybrid Mandibular Advancement and Tongue-Stabilizing Devices
What This Type Is
This is the newest category in the anti-snoring market, and the smallest. A hybrid device combines a mandibular advancement design with a tongue-stabilizing element in the same mouthpiece. The thinking is that in some snorers both jaw posture and tongue posture meaningfully contribute, so addressing one mechanism leaves residual snoring that addressing both could quiet. For the right person, the combined approach is appealing. For most people, a well-fitted MAD on its own is enough.
Top Pick: Snorple
The clearest pick in this category is Snorple, which markets itself as a hybrid mouthpiece combining mandibular advancement with a tongue-stabilizing element. The advancement system offers nine adjustable positions, the fit is boil-and-bite, and the brand promotes a 100-night money-back guarantee that it claims is the longest trial period in the anti-snoring category. That generous trial window is genuinely helpful in a product category where the only honest way to test fit is to sleep in the device for a few weeks.
Where this category falls short is in the independent evidence base. Hybrid devices are newer than MADs or pure tongue-stabilizing devices, and the peer-reviewed research on the combined form factor specifically is much thinner than for either mechanism on its own. User reviews of Snorple are generally positive, and the engineering rationale for combining both mechanisms is sensible, but the honest framing is this: hybrids are a reasonable category to try if a basic MAD has given you partial but incomplete relief, or if you suspect your tongue posture is a meaningful contributor to your snoring. They are not necessarily the first device to reach for if you have never tried a mouthpiece before.
How To Choose Between the Types
When you are sitting between several open browser tabs, a comparison usually helps. The table below summarizes the categories at the level of decision you actually need to make.
Category
Best For
Fit Method
Typical Price
Main Trade-Off
Boil-and-bite adjustable MAD
Most first-time buyers who want a fitted feel without seeing a dentist
Soften in hot water and mold to your teeth
Around $70–$100
Mild jaw soreness during the first week; needs a slow titration
Pre-formed multi-size MAD
People who want no setup or a travel-friendly backup
Pick a size from the included options
Around $70–$100
Less personalized fit; only one of two fixed advancement positions
Custom dentist-fitted MAD
Persistent or severe snorers; anyone with possible sleep apnea
Lab-made from dental impressions or a digital scan
Around $1,500–$3,000 out of pocket
Cost, time, and access to a sleep dentist
Tongue-stabilizing device
Denture wearers, TMJ disorder, or tongue-driven snoring
No fitting required
Around $90–$130
First-week tongue soreness; more modest evidence base than MADs
Hybrid MAD plus tongue-stabilizing
People for whom a MAD alone gave partial relief
Boil-and-bite
Around $130–$170
Less independent clinical evidence on hybrid form factor
A quick way to use this is to start at the category that matches your situation most cleanly, look up the top pick for that category in the section above, and then check whether the trade-off is one you can live with. If the answer is yes, take advantage of the trial window. If the trade-off is a deal-breaker, move one category over.
Tip
If you have not tried a mouthpiece before, a boil-and-bite adjustable MAD is the right starting point for most snorers. It gives you the best combination of personalized fit and reasonable price, and the titration mechanism lets you find the smallest amount of advancement that solves the problem rather than overcorrecting from the start.
When a Mouth Guard Isn't Enough
A mouthpiece is the right answer for primary snoring — the noise problem, without the underlying breathing-disordered sleep. It is not the right answer for obstructive sleep apnea, which is a different condition with real cardiovascular consequences. Knowing the difference matters because the symptoms can overlap, and a quiet, well-fitted mouthpiece can mask the warning signs of apnea while leaving the underlying condition untreated.
There are specific contraindications that mean a mandibular advancement device is the wrong choice for you, full stop. The FDA's special controls guidance for intraoral devices for snoring and obstructive sleep apnea highlights active temporomandibular joint disorders, loose teeth or advanced periodontal disease, insufficient healthy teeth to support a device, and central sleep apnea as situations where MADs are not appropriate. The first two are fairly self-explanatory: a device that puts forward pressure on the teeth and jaw can aggravate existing problems quickly. The third matters because MADs need enough healthy dental real estate to grip safely; fewer than roughly eight to ten healthy teeth in either arch usually rules them out. And the fourth matters because mandibular advancement helps with anatomic airway obstruction, not with central sleep apnea, where the brain stops sending the signal to breathe.
There are also red flags that should send you to a sleep physician rather than to another mouthpiece. According to the Sleep Foundation's overview of sleep apnea symptoms, the classic warning signs include loud habitual snoring combined with witnessed pauses in breathing, choking or gasping during sleep, excessive daytime sleepiness, morning headaches, and hard-to-control high blood pressure or known cardiovascular disease. If you recognize yourself or your partner in any of these, please do not pick another mouthpiece off a shopping list. Talk to your primary care doctor, ask about a sleep study, and let a clinician sort out what is actually going on. A custom-fitted appliance prescribed by a dental sleep medicine provider is a perfectly reasonable next step after that conversation; an over-the-counter device is not.
Even when a mouthpiece is the right tool, it comes with side effects worth disclosing plainly. Jaw soreness, tooth tenderness, increased salivation, and sometimes dry mouth are common in the first one to two weeks of use. They usually settle down. Long-term use of a mandibular advancement device can also cause subtle, gradual changes in your bite, which is exactly why custom-fitted appliances include scheduled follow-ups with your dentist. If you are using an over-the-counter device for more than a few months, it is worth mentioning to your regular dentist at your next cleaning so they can watch for any drift in your bite position.
About the Author
Angela Nightingale
Senior Editor
Angela Nightingale is a Senior Editor at Daily Vitality with over two decades of experience in digital publishing and health and wellness content. She specializes in turning complex, often-confusing health topics into clear, calm, and practical guidance that respects the reader's intelligence. Her work focuses on helping people feel informed and confident — never overwhelmed or alarmed — as they make everyday decisions about how they eat, move, rest, and age.
For most snorers, yes — with real caveats. Peer-reviewed clinical evidence supports mandibular advancement devices as an effective treatment for both primary snoring and mild-to-moderate obstructive sleep apnea, with typical reductions in the apnea-hypopnea index of roughly 40% to 60% from baseline and high rates of snoring reduction in primary snoring. Custom dentist-fitted devices outperform over-the-counter devices on average, but well-designed over-the-counter MADs help a large share of straightforward snorers.
It matters. FDA-cleared means the device went through the 510(k) pathway, showing it is substantially equivalent to a device already on the market. FDA-approved is a stricter standard that most over-the-counter anti-snoring mouthpieces have not been through. Both indicate FDA oversight, but only one applies to most snoring mouth guards. If a brand uses "FDA-approved" loosely on its marketing, that is a small red flag for how carefully they handle other claims.
Generally no. Mandibular advancement devices physically move the lower jaw forward, which can aggravate temporomandibular joint pain and dysfunction. If you have diagnosed TMJ disorder, you should either avoid MADs entirely or only use a custom-fitted device under the supervision of a dentist with dental sleep medicine training. A tongue-stabilizing device is usually the safer over-the-counter choice in this situation because it does not move the jaw.
Over-the-counter MADs typically last between six and eighteen months with regular use and proper cleaning. Custom dentist-fitted appliances typically last three to five years. Tongue-stabilizing devices typically last about twelve months. Replace any device sooner if you notice cracks, persistent odor that will not clean off, or a change in fit.
If a partner has witnessed you stop breathing, choke, or gasp during sleep; if you are excessively sleepy during the day; if you have morning headaches or hard-to-control high blood pressure; or if loud snoring continues after 30 nights of using a properly fitted MAD. Those are the classic signs of obstructive sleep apnea, which needs a sleep study and a physician's care rather than another mouthpiece.
Often, yes — and back-sleepers tend to be the group that benefits most. Back sleeping increases snoring because gravity pulls the tongue further into the back of the throat and partially blocks the airway. A mouthpiece that holds the jaw or tongue forward counteracts that mechanism directly. If you snore mostly when sleeping on your back, adding a side-sleeping habit or a positional pillow alongside the mouthpiece often improves results further.
For mild to moderate obstructive sleep apnea, custom-fitted oral appliance therapy prescribed by a dental sleep medicine provider is an evidence-supported alternative when CPAP is not tolerated, and the joint clinical practice guideline from the American Academy of Sleep Medicine and the American Academy of Dental Sleep Medicine recognizes this. Over-the-counter mouthpieces are a different category. They are cleared by the FDA for snoring, and some are cleared for mild OSA specifically, but they are not a substitute for a clinical evaluation if sleep apnea is suspected.
Long-term use of any mandibular advancement device can lead to subtle, gradual changes in tooth position and bite alignment. This is well-documented in the dental sleep medicine literature and is exactly why custom-fitted appliances include scheduled follow-ups with a dentist. If you are using an over-the-counter device on an ongoing basis, mention it at your regular cleanings so your dentist can monitor for any drift.
A mandibular advancement device generally cannot be used safely with full dentures because there is no stable dental structure for the device to grip. A tongue-stabilizing device, which does not interact with your teeth at all, is usually the right over-the-counter choice in this situation. Your dentist may also be able to fit a custom oral appliance designed to work with a partial denture or with implants — that is a conversation to have at a regular dental visit.
Rinse your device with cool water in the morning, then brush it gently with a soft toothbrush and a mild non-abrasive cleanser. Avoid hot water on devices that were heat-molded, since heat can deform them. Most manufacturers recommend a weekly soak in a denture-cleaning tablet to keep the device fresh. Store it dry in the case that came with it, since damp storage encourages odor and discoloration.
Give it the full trial window — usually at least two to four weeks — before deciding the device is not working. Snoring patterns vary night to night, and most mouthpieces need a few nights of adjustment before they reach their full effect. If the snoring genuinely has not improved after 30 nights at the appropriate advancement setting, that is a meaningful signal. Either the device is not the right type for your particular anatomy, or your snoring may be driven by something a mouthpiece cannot address, in which case a sleep specialist is the right next step.
Sources
American Academy of Sleep Medicine and American Academy of Dental Sleep Medicine. Clinical Practice Guideline for the Treatment of Obstructive Sleep Apnea and Snoring with Oral Appliance Therapy. Retrieved from https://www.aasm.org/
American Academy of Sleep Medicine. Practice Parameters and Review of Oral Appliance Therapy for OSA. Retrieved from https://www.aasm.org/
American Academy of Dental Sleep Medicine. Oral Appliance Therapy for Obstructive Sleep Apnea. Retrieved from https://www.aadsm.org/
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American Dental Association. Evidence Brief on Oral Appliances for Sleep-Related Breathing Disorders. Retrieved from https://www.ada.org/
U.S. Food and Drug Administration. Intraoral Devices for Snoring and/or Obstructive Sleep Apnea — Class II Special Controls Guidance Document. Retrieved from https://www.fda.gov/
Code of Federal Regulations, Title 21. Section 872.5575 — Intraoral Devices for Snoring and/or Obstructive Sleep Apnea. Retrieved from https://www.govregs.com/
Long-term Efficacy of Mandibular Advancement Devices in the Treatment of Adult Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis. Retrieved from https://pmc.ncbi.nlm.nih.gov/