I want to be careful here, because this is exactly the territory where health content tends to overpromise.
The clearest statement available comes from the National Institute on Aging, and it is worth taking at face value: there are currently no drugs or lifestyle approaches proven to prevent Alzheimer's disease or a related dementia. The NIA also cautions specifically about pills, supplements, and brain-training games marketed as memory boosters or dementia preventers, noting that these may be unsafe, a waste of money, or both, and that some can interfere with other medical treatments. If you take one practical thing from this article, that might reasonably be it.
What the evidence does support is risk reduction, which is a more modest claim and a real one. The 2024 Lancet standing Commission on dementia prevention identified 14 modifiable risk factors associated with roughly 45% of dementia cases worldwide: low education, hearing loss, high blood pressure, smoking, obesity, depression, physical inactivity, diabetes, excessive alcohol, traumatic brain injury, air pollution, social isolation, high LDL cholesterol, and untreated vision loss.
Two of those deserve a moment because they are so easy to overlook. Hearing loss and untreated vision loss are routinely treated as cosmetic inconveniences rather than health issues, and getting your hearing checked is not a small thing.
It is worth being clear about what these numbers mean. They are population-level associations, not individual guarantees, and nothing on that list is a lever that reliably produces an outcome for any one person. Addressing them is also not a verdict on anyone already living with dementia — no one causes this through their choices. If you would like the practical version, our piece on cognitive health habits the research actually supports goes through them one at a time.