What the Researchers Measured
In 2015, three researchers at Dartmouth took the proverb at its word. Using the National Health and Nutrition Examination Survey (NHANES) from 2007–2008 and 2009–2010, they looked at 8,399 US adults who had described everything they ate over a 24-hour period. Of those, 753 people, or 9.0%, counted as daily apple eaters, meaning they ate at least the equivalent of one small apple (149 grams of raw apple) that day, as reported in JAMA Internal Medicine.
The researchers gave "keeping the doctor away" a concrete definition: no more than one self-reported visit to a physician in the past year. They also looked at three other kinds of health care, namely overnight hospital stays, visits to a mental health professional, and prescription medications.
One detail matters for later. People whose apple intake came entirely from juice or applesauce, 329 of them, were left out of the main analysis. This was a study of whole apples.
The paper ran in the journal's first April Fools'-themed issue, which explains the playful title. The analysis itself, though, was entirely serious, and Harvard's health publishing team described it at the time as an apple a day may not keep the doctor away, but it's a healthy choice anyway.
What They Found
At first glance, the proverb looked like it might hold up. In the raw numbers, 39.0% of apple eaters kept the doctor away, compared with 33.9% of everyone else. That gap was statistically significant.
Then the researchers did what careful researchers do. They adjusted for the ways apple eaters differed from non-eaters, including age, sex, education, income, marital status, body mass index, self-rated health, smoking, and health insurance. Once those differences were accounted for, the apple advantage shrank and was no longer statistically significant. Apple eaters were no more likely than anyone else to avoid hospital stays or mental health visits either.
The authors' conclusion was plain: the evidence does not support the idea that an apple a day keeps the doctor away.
A cross-sectional survey like this one captures a single snapshot in time. It can show that two things travel together, but it cannot show that one caused the other. The authors flagged this themselves, along with the fact that one day of eating is only a glimpse of someone's usual diet and that doctor visits were self-reported.